Details
- scope
- mouse GPe in vivo, juxtacellular recording-labelling during head-fixed locomotion
- section_id
- section_05
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
- effect_size
- distinct developmental origins; arkypallidal robustly increase firing during movement, prototypic heterogeneously decrease
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-05
- source_kind
- review_finding
- source_path
- evidence/section_05_evidence_package.json
- source_span
- Taking the results of our four complementary fate-mapping experiments together, we conclude that prototypic GPe neurons are derived from the MGE, whereas arkypallidal neurons are derived from the LGE/CGE ( F).
- study_system
- mouse GPe in vivo, juxtacellular recording-labelling during head-fixed locomotion
- section_title
- Pallidal Organization and the Disinhibition Principle
- evidence_summary
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-05
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
- claim_text
Prototypic and arkypallidal GPe neurons originate from distinct embryonic eminences (MGE vs LGE/CGE) and show distinct in vivo firing during voluntary movement — prototypic neurons heterogeneously decrease firing while arkypallidal neurons robustly increase firing.
- raw_fields
{ "n": 0, "doi": "10.1016/j.neuron.2015.03.007", "claim": "Prototypic and arkypallidal GPe neurons originate from distinct embryonic eminences (MGE vs LGE/CGE) and show distinct in vivo firing during voluntary movement — prototypic neurons heterogeneously decrease firing while arkypallidal neurons robustly increase firing.", "cite_key": "Dodson2015", "evidence": "", "effect_size": "distinct developmental origins; arkypallidal robustly increase firing during movement, prototypic heterogeneously decrease", "text_access": "fulltext", "study_system": "mouse GPe in vivo, juxtacellular recording-labelling during head-fixed locomotion", "source_cluster_id": "cluster_04", "replication_status": "replicated", "claim_source_sentence": "Taking the results of our four complementary fate-mapping experiments together, we conclude that prototypic GPe neurons are derived from the MGE, whereas arkypallidal neurons are derived from the LGE/CGE ( F).", "replication_evidence_dois": [ "10.1016/j.neuron.2012.04.027", "10.1523/jneurosci.4662-14.2015" ], "effect_size_source_sentence": "These neurons fire at high rates during alert rest, and encode movements through heterogeneous firing rate changes, with many neurons decreasing their activity." }- source_refs
[ "paper:paper-4c9b05cf8ee7" ]
- evidence_refs
[ { "ref": "paper:paper-4c9b05cf8ee7" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }