Synthesis of cortico-striatal connectivity data supports a 'disclosed loop' fra…

Synthesis of cortico-striatal connectivity data supports a 'disclosed loop' framework in which a closed re-entrant loop is open to outside influence at the level of cortical input: striatal output channels are topographically narrow on frontal cortices, while striatal inputs originate from a far broader cortical span and diverge widely in striatal termination.

{
  "n": null,
  "doi": "10.1007/s00429-016-1250-9",
  "claim": "Synthesis of cortico-striatal connectivity data supports a 'disclosed loop' framework in which a closed re-entrant loop is open to outside influence at the level of cortical input: striatal output channels are topographically narrow on frontal cortices, while striatal inputs originate from a far broader cortical span and diverge widely in striatal termination.",
  "cite_key": "Shipp2016a",
  "evidence": "Theoretical synthesis of anatomical and physiological data on cortico-BG loop topology.",
  "effect_size": "qualitative",
  "text_access": "fulltext",
  "study_system": "rodent + primate (review)",
  "source_cluster_id": "cluster_03",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Input–output architecture of the striatum The disclosed loop thesis is that no part of the striatum lacks a component of operative input, conveying a bid for action selection.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Re-entrant signals traversing the cortico-BG loop impact predominantly frontal cortices, conveyed through topographically ordered output channels; by contrast, striatal input signals originate from a far broader span of cortex, and are far more divergent in their termination."
}

[
  "paper:paper-8bdeb3d1c454"
]

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    "ref": "paper:paper-8bdeb3d1c454"
  }
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  "notes": [
    "Local review repositories are read-only inputs.",
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  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
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