Details

scope
pilocarpine-treated epileptic mice, silicon probes + miniscope
claim_text
Epileptic mice show desynchronized interneuron firing between CA1 and dentate gyrus; CA1 place cells become unstable and completely remap across a week, emerging ~6 weeks after status epilepticus
section_id
section_10_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json
effect_size
Place cell instability emerged around 6 weeks after status epilepticus, well after onset of chronic seizures
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-10
source_kind
review_finding
source_path
evidence/section_10_evidence_package.json
source_span
We found desynchronized interneuron firing between the CA1 and dentate gyrus in epileptic mice.
study_system
pilocarpine-treated epileptic mice, silicon probes + miniscope
section_title
Oscillations and Network Dynamics: Gamma, Ripples, and Synchrony
evidence_summary
Epileptic mice show desynchronized interneuron firing between CA1 and dentate gyrus; CA1 place cells become unstable and completely remap across a week, emerging ~6 weeks after status epilepticus
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-10
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1038/s41593-019-0559-0",
  "claim": "Epileptic mice show desynchronized interneuron firing between CA1 and dentate gyrus; CA1 place cells become unstable and completely remap across a week, emerging ~6 weeks after status epilepticus",
  "evidence": "Epileptic mice show desynchronized interneuron firing between CA1 and dentate gyrus; CA1 place cells become unstable and completely remap across a week, emerging ~6 weeks after status epilepticus",
  "effect_size": "Place cell instability emerged around 6 weeks after status epilepticus, well after onset of chronic seizures",
  "text_access": "fulltext",
  "study_system": "pilocarpine-treated epileptic mice, silicon probes + miniscope",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We found desynchronized interneuron firing between the CA1 and dentate gyrus in epileptic mice.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "This spatial instability emerged around 6 weeks after status epilepticus, well after the onset of chronic seizures and interneuron death."
}
source_refs
[
  "paper:paper-7ad0fc4f2f75"
]
evidence_refs
[
  {
    "ref": "paper:paper-7ad0fc4f2f75"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.