In mouse prelimbic prefrontal cortex, callosal inputs evoke much stronger monos…

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scope: mouse prelimbic prefrontal cortex, L5 CC and CT neurons
claim_text: In mouse prelimbic prefrontal cortex, callosal inputs evoke much stronger monosynaptic excitation onto L5 cortico-thalamic (CT) projection neurons than onto neighboring intratelencephalic cortico-cortical (CC/IT) neurons.
section_id: section_07
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
effect_size: qualitative — much stronger callosal EPSC at CT vs CC
review_repo: ComputationalReviewRecurrence
section_ref: wiki_page:computationalreviewrecurrence-07-celltype-motifs
source_kind: review_finding
source_path: evidence/section_07_evidence_package.json
source_span: We find callosally evoked excitation and feedforward inhibition are much stronger at CT neurons compared to neighboring CC neurons.
study_system: mouse prelimbic prefrontal cortex, L5 CC and CT neurons
section_title: 7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity
evidence_summary: Optogenetic stimulation of callosal axons combined with whole-cell patch-clamp recordings of retrogradely identified L5 CC (IT) and CT neurons.
review_bundle_ref: analysis_bundle:ab-d9c479db9be9
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-d9c479db9be9
source_artifact_ref: wiki_page:computationalreviewrecurrence-07-celltype-motifs
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
commit_sha: 79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1016/j.celrep.2017.12.073",
  "claim": "In mouse prelimbic prefrontal cortex, callosal inputs evoke much stronger monosynaptic excitation onto L5 cortico-thalamic (CT) projection neurons than onto neighboring intratelencephalic cortico-cortical (CC/IT) neurons.",
  "cite_key": "Anastasiades2018",
  "evidence": "Optogenetic stimulation of callosal axons combined with whole-cell patch-clamp recordings of retrogradely identified L5 CC (IT) and CT neurons.",
  "effect_size": "qualitative — much stronger callosal EPSC at CT vs CC",
  "text_access": "abstract_only",
  "study_system": "mouse prelimbic prefrontal cortex, L5 CC and CT neurons",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We find callosally evoked excitation and feedforward inhibition are much stronger at CT neurons compared to neighboring CC neurons.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-ec6edc3ce25f"
]

evidence_refs

[
  {
    "ref": "paper:paper-ec6edc3ce25f"
  }
]

source_policy

{
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  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

In mouse prelimbic prefrontal cortex, callosal inputs evoke much stronger monos…

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