- claim_text
Deep brain stimulation of basal ganglia output nodes (STN, GPi) provides marked motor benefit in Parkinson's disease but the precise mechanism remains uncertain, illustrating that effective therapeutic targets do not yet uniquely select among competing circuit models.
- raw_fields
{
"n": 0,
"doi": "10.1146/annurev.neuro.29.051605.112824",
"claim": "Deep brain stimulation of basal ganglia output nodes (STN, GPi) provides marked motor benefit in Parkinson's disease but the precise mechanism remains uncertain, illustrating that effective therapeutic targets do not yet uniquely select among competing circuit models.",
"cite_key": "Perlmutter2006",
"evidence": "",
"effect_size": "",
"text_access": "abstract_only",
"study_system": "human DBS clinical and mechanistic review",
"source_cluster_id": "cluster_04",
"replication_status": "replication_unknown",
"claim_source_sentence": "Stimulation of the ventral intermediate nucleus of the thalamus can dramatically relieve tremor associated with essential tremor or Parkinson disease (PD).",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-c0c39d4c984a"
]
- evidence_refs
[
{
"ref": "paper:paper-c0c39d4c984a"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}