GABA-A receptor alpha1 subunit is colocalized at postsynaptic sites of axo-axon…

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scope: mouse piriform cortex, immunohistochemistry
claim_text: GABA-A receptor alpha1 subunit is colocalized at postsynaptic sites of axo-axonic synapses in piriform cortex
section_id: section_06_evidence_package
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
review_repo: ComputationalReviewPV
section_ref: wiki_page:computationalreviewpv-06
source_kind: review_finding
source_path: evidence/section_06_evidence_package.json
source_span: gephyrin, Na-K-2Cl cotransporter 1, and GABA(A) receptor alpha1 subunit, but not K-Cl cotransporter 2, are colocalized at the presumed postsynaptic sites.
study_system: mouse piriform cortex, immunohistochemistry
section_title: Synaptic Physiology: Input Specificity, Output Targeting, and Short-Term Dynamics
evidence_summary: Presynaptic sites contain GAD67, VGAT, and parvalbumin but not calbindin; NKCC1 but not KCC2 at postsynaptic sites
review_bundle_ref: analysis_bundle:ab-e6261c8263e7
replication_status: independently_replicated
review_package_ref: analysis_bundle:ab-e6261c8263e7
source_artifact_ref: wiki_page:computationalreviewpv-06
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
commit_sha: df9fc7e8d455b084152c9d713558dae0013cef21
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1002/cne.22792",
  "claim": "GABA-A receptor alpha1 subunit is colocalized at postsynaptic sites of axo-axonic synapses in piriform cortex",
  "evidence": "Presynaptic sites contain GAD67, VGAT, and parvalbumin but not calbindin; NKCC1 but not KCC2 at postsynaptic sites",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse piriform cortex, immunohistochemistry",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "gephyrin, Na-K-2Cl cotransporter 1, and GABA(A) receptor alpha1 subunit, but not K-Cl cotransporter 2, are colocalized at the presumed postsynaptic sites.",
  "replication_evidence_dois": [
    "10.1038/nature08928",
    "10.1126/sciadv.adv0588"
  ],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-03615224c1d6"
]

evidence_refs

[
  {
    "ref": "paper:paper-03615224c1d6"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

GABA-A receptor alpha1 subunit is colocalized at postsynaptic sites of axo-axon…

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