Details

scope
mouse hippocampus CA1, in vitro and in vivo
claim_text
PV basket cells evoke greater inhibition in deep versus superficial CA1 pyramidal cells, and further segregate among deep PCs by preferentially innervating amygdala-projecting PCs but receiving excitation from PFC-projecting PCs
section_id
section_07_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
effect_size
Deep PCs receive greater PV inhibition than superficial PCs; projection-specific connectivity bias
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-07
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
study_system
mouse hippocampus CA1, in vitro and in vivo
section_title
Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward
evidence_summary
Paired recordings in vitro, 2-photon calcium imaging in vivo, and computational modeling
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
single study
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-07
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1016/j.neuron.2014.03.034",
  "claim": "PV basket cells evoke greater inhibition in deep versus superficial CA1 pyramidal cells, and further segregate among deep PCs by preferentially innervating amygdala-projecting PCs but receiving excitation from PFC-projecting PCs",
  "evidence": "Paired recordings in vitro, 2-photon calcium imaging in vivo, and computational modeling",
  "effect_size": "Deep PCs receive greater PV inhibition than superficial PCs; projection-specific connectivity bias",
  "text_access": "fulltext",
  "study_system": "mouse hippocampus CA1, in vitro and in vivo",
  "replication_status": "single study",
  "claim_source_sentence": "Parvalbumin-expressing basket cells (PVBCs) evoked greater inhibition in CA1 PCs located in the deep compared to superficial layer of stratum pyramidale. Additionally, PVBCs further segregated among deep PCs, preferentially innervating the amygdala-projecting PCs but receiving preferential excitation from the prefrontal cortex-projecting PCs, thus revealing distinct perisomatic inhibitory interactions between separate output channels.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Parvalbumin-expressing basket cells (PVBCs) evoked greater inhibition in CA1 PCs located in the deep compared to superficial layer of stratum pyramidale."
}
source_refs
[
  "paper:paper-722a8aa86ab1"
]
source_span
Parvalbumin-expressing basket cells (PVBCs) evoked greater inhibition in CA1 PCs located in the deep compared to superficial layer of stratum pyramidale. Additionally, PVBCs further segregated among deep PCs, preferentially innervating the amygdala-projecting PCs but receiving preferential excitation from the prefrontal cortex-projecting PCs, thus revealing distinct perisomatic inhibitory interactions between separa...
evidence_refs
[
  {
    "ref": "paper:paper-722a8aa86ab1"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.