Details

scope
Patients with schizophrenia, bipolar I, bipolar II, MDD, and matched healthy controls
section_id
section_14
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-14
source_kind
review_finding
source_path
evidence/section_14_evidence_package.json
source_span
Conclusion Our findings provide FC evidence that supports the common network hypothesis by identifying common thalamocortical dysconnectivities across 4 major psychiatric disorders.
study_system
Patients with schizophrenia, bipolar I, bipolar II, MDD, and matched healthy controls
section_title
Loop Dysfunction in Neurological and Psychiatric Disease
evidence_summary
Resting-state fMRI in 100 schizophrenia, 100 bipolar I, 88 bipolar II, 100 MDD, 160 controls; conjunction analysis.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-14
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
claim_text
Schizophrenia, bipolar I, bipolar II, and major depressive disorder share a common thalamocortical dysconnectivity pattern: decreased FC with prefrontal/parietal salience-network regions and increased FC with sensorimotor and temporal cortex.
raw_fields
{
  "n": 548,
  "doi": "10.1093/schbul/sby166",
  "claim": "Schizophrenia, bipolar I, bipolar II, and major depressive disorder share a common thalamocortical dysconnectivity pattern: decreased FC with prefrontal/parietal salience-network regions and increased FC with sensorimotor and temporal cortex.",
  "cite_key": "Tu2018",
  "evidence": "Resting-state fMRI in 100 schizophrenia, 100 bipolar I, 88 bipolar II, 100 MDD, 160 controls; conjunction analysis.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "Patients with schizophrenia, bipolar I, bipolar II, MDD, and matched healthy controls",
  "source_cluster_id": "cluster_13",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Conclusion Our findings provide FC evidence that supports the common network hypothesis by identifying common thalamocortical dysconnectivities across 4 major psychiatric disorders.",
  "replication_evidence_dois": [
    "10.1016/j.bpsc.2019.04.012",
    "10.1016/j.jaac.2020.07.903"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-823c98ee884d"
]
evidence_refs
[
  {
    "ref": "paper:paper-823c98ee884d"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.