Details

scope
rodent and primate striatum, narrative review
claim_text
Striatal output is shaped by a triumvirate of projecting/aspiny neurons (PANs/SPNs), tonically active cholinergic interneurons (TANs) and fast-spiking parvalbumin interneurons (FSIs) acting on overlapping but distinct timescales
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
effect_size
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-05
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
study_system
rodent and primate striatum, narrative review
section_title
Pallidal Organization and the Disinhibition Principle
evidence_summary
Synthesis of striatal interneuron physiology and connectivity literature
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-05
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.3389/fncel.2025.1572657",
  "claim": "Striatal output is shaped by a triumvirate of projecting/aspiny neurons (PANs/SPNs), tonically active cholinergic interneurons (TANs) and fast-spiking parvalbumin interneurons (FSIs) acting on overlapping but distinct timescales",
  "cite_key": "Apicella2025",
  "evidence": "Synthesis of striatal interneuron physiology and connectivity literature",
  "effect_size": "",
  "text_access": "fulltext",
  "study_system": "rodent and primate striatum, narrative review",
  "source_cluster_id": "cluster_04",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Functional classification of neuronal types in the striatum In the early 1980s, electrophysiological studies in behaving monkeys began to differentiate between two main types of neurons within the striatum, termed phasically active neurons (PANs) and tonically active neurons (TANs), presumed to be GABAergic projection neurons and cholinergic interneurons, respectively ( ; ).",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-f83e9ad861d8"
]
source_span
Functional classification of neuronal types in the striatum In the early 1980s, electrophysiological studies in behaving monkeys began to differentiate between two main types of neurons within the striatum, termed phasically active neurons (PANs) and tonically active neurons (TANs), presumed to be GABAergic projection neurons and cholinergic interneurons, respectively ( ; ).
evidence_refs
[
  {
    "ref": "paper:paper-f83e9ad861d8"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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