Details

scope
cat, ATN
claim_text
Time to retire the serial Papez circuit: Implications for space, memory, and attention
section_id
section_06
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-06
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
source_span
As part of this reformulation, we show that the anterior thalamic nuclei support a variety of functions (including mnemonic, spatial, and aspects of attention), some of which appear to be independent of the hippocampus.
study_system
cat, ATN
section_title
Thalamic Feedback: Closing the Loop
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-06
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1016/j.neubiorev.2022.104813",
  "claim": "Time to retire the serial Papez circuit: Implications for space, memory, and attention",
  "cite_key": "Aggleton2022",
  "evidence": "After more than 80 years, Papez serial circuit remains a hugely influential concept, initially for emotion, but in more recent decades, for memory. Here, we show how this circuit is anatomically and mechanistically naïve as well as outdated. We argue that a new conceptualisation is necessitated by recent anatomical and functional findings that emphasize the more equal, working partnerships between",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "cat, ATN",
  "source_cluster_id": "cluster_05",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "As part of this reformulation, we show that the anterior thalamic nuclei support a variety of functions (including mnemonic, spatial, and aspects of attention), some of which appear to be independent of the hippocampus.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-cc60b377cc23"
]
evidence_refs
[
  {
    "ref": "paper:paper-cc60b377cc23"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}
evidence_summary
After more than 80 years, Papez serial circuit remains a hugely influential concept, initially for emotion, but in more recent decades, for memory. Here, we show how this circuit is anatomically and mechanistically naïve as well as outdated. We argue that a new conceptualisation is necessitated by recent anatomical and functional findings that emphasize the more equal, working partnerships between

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