Version history

{
  "scope": "mouse hippocampus",
  "claim_text": "A common finding between different cortical regions is that VIP+ IS cells suppress some local interneuron activity during complex behaviours, including visual processing 12 , 14 , 16 , locomotion 13 and reward-associated learning 17 , thus leading to network disinhibition.",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/s41467-018-07162-5",
    "year": "2018",
    "claim": "A common finding between different cortical regions is that VIP+ IS cells suppress some local interneuron activity during complex behaviours, including visual processing 12 , 14 , 16 , locomotion 13 and reward-associated learning 17 , thus leading to network disinhibition.",
    "title": null,
    "journal": "Nature communications",
    "cite_key": "Francavilla2018a",
    "evidence": "Connectivity and network state-dependent recruitment of long-range VIP-GABAergic neurons in the mouse hippocampus",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "mouse hippocampus",
    "_source_cluster": "cluster_06_disinhibition_circuit",
    "replication_status": "replicated",
    "_source_cluster_index": 43,
    "claim_source_sentence": "A common finding between different cortical regions is that VIP+ IS cells suppress some local interneuron activity during complex behaviours, including visual processing 12 , 14 , 16 , locomotion 13 and reward-associated learning 17 , thus leading to network disinhibition.",
    "replication_evidence_dois": [
      "10.1038/nn.3544",
      "10.1126/science.1254126",
      "10.1038/nn.4554"
    ],
    "effect_size_source_sentence": "Interestingly, anatomical data point to the existence of long-range circuit elements that could account for cross-regional disinhibition between the hippocampus and functionally connected areas: CA1 SOM- or muscarinic receptor 2 (M2R)-expressing GABAergic cells innervate hippocampal inhibitory interneurons and can project to several cortical and sub-cortical areas, including the rhinal and retrosplenial cortices, subiculum (SUB) and medial septum (MS) 26 – 30 ."
  },
  "section_id": "section_12",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-12-computational-models",
  "source_kind": "review_finding",
  "source_path": "evidence/section_12_evidence_package.json",
  "source_refs": [
    "paper:paper-c5dc6d520729"
  ],
  "source_span": "A common finding between different cortical regions is that VIP+ IS cells suppress some local interneuron activity during complex behaviours, including visual processing 12 , 14 , 16 , locomotion 13 and reward-associated learning 17 , thus leading to network disinhibition.",
  "study_system": "mouse hippocampus",
  "evidence_refs": [
    {
      "ref": "paper:paper-c5dc6d520729"
    }
  ],
  "section_title": "Computational Models of VIP Circuit Function",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Connectivity and network state-dependent recruitment of long-range VIP-GABAergic neurons in the mouse hippocampus",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-12-computational-models",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}