Details

scope
amniote (cross-species)
claim_text
This pattern suggests that divergence among cell types across species may be driven by species-specific DEGs, while shared DEGs likely preserve fundamental cell type identities.
section_id
section_15
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_15_evidence_package.json
effect_size
12 species
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-15
source_kind
review_finding
source_path
evidence/section_15_evidence_package.json
source_span
This pattern suggests that divergence among cell types across species may be driven by species-specific DEGs, while shared DEGs likely preserve fundamental cell type identities.
study_system
amniote (cross-species)
section_title
Species Differences and Evolutionary Scaling of Loop Architecture
evidence_summary
fulltext
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-15
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_15_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 12,
  "doi": "10.24272/j.issn.2095-8137.2024.102",
  "claim": "This pattern suggests that divergence among cell types across species may be driven by species-specific DEGs, while shared DEGs likely preserve fundamental cell type identities.",
  "cite_key": "Fu2025",
  "evidence": "fulltext",
  "effect_size": "12 species",
  "text_access": "fulltext",
  "study_system": "amniote (cross-species)",
  "source_cluster_id": "cluster_14",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "This pattern suggests that divergence among cell types across species may be driven by species-specific DEGs, while shared DEGs likely preserve fundamental cell type identities.",
  "replication_evidence_dois": [
    "10.1126/science.ade9516",
    "10.1038/s41586-023-06812-z"
  ],
  "effect_size_source_sentence": "Protein sequence alignment of STAT6 across 12 species revealed high conservation among mammals, with the platypus exhibiting greater sequence similarity to other mammals than to avians, lizards, crocodiles, turtles, and frogs (internally conservative) ( Figure 5I )."
}
source_refs
[
  "paper:paper-e7ab2bed6ce4"
]
evidence_refs
[
  {
    "ref": "paper:paper-e7ab2bed6ce4"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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