Version history

{
  "scope": "mouse somatosensory cortex; immunohistochemistry + 5HT3aR-BAC reporter",
  "claim_text": "Rudy, Fishell, Lee, & Hjerling-Leffler (2011) established that PV-, SST-, and 5HT3aR-expressing neurons together account for nearly 100% of neocortical GABAergic interneurons, with 5HT3aR group containing all VIP+ neurons (~40%) and a non-VIP neurogliaform subgroup.",
  "raw_fields": {
    "n": null,
    "doi": "10.1002/dneu.20853",
    "claim": "Rudy, Fishell, Lee, & Hjerling-Leffler (2011) established that PV-, SST-, and 5HT3aR-expressing neurons together account for nearly 100% of neocortical GABAergic interneurons, with 5HT3aR group containing all VIP+ neurons (~40%) and a non-VIP neurogliaform subgroup.",
    "title": null,
    "cite_key": "Rudy2011",
    "evidence": "Triple-marker (PV/SST/5HT3aR) cytometric scheme accounts for ~100% mouse S1 GABAergic interneurons; 5HT3aR group ~30% of total INs; ~40% of 5HT3aR group express VIP; PV/SST/VIP non-overlapping major classes.",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "mouse somatosensory cortex; immunohistochemistry + 5HT3aR-BAC reporter",
    "target_section": "section_02",
    "_source_cluster": "cluster_01_molecular_taxonomy",
    "replication_status": "replicated",
    "_source_cluster_index": 21,
    "claim_source_sentence": "The 5HT3aR group, which also accounts for ~30% of the total interneuronal population, is heterogeneous and includes all of the neurons that express the neuropeptide VIP, as well as an equally numerous subgroup of neurons that do not express VIP and includes neurogliaform cells."
  },
  "section_id": "section_02",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-02-classification",
  "source_kind": "review_finding",
  "source_path": "evidence/section_02_evidence_package.json",
  "source_refs": [
    "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
  ],
  "source_span": "The 5HT3aR group, which also accounts for ~30% of the total interneuronal population, is heterogeneous and includes all of the neurons that express the neuropeptide VIP, as well as an equally numerous subgroup of neurons that do not express VIP and includes neurogliaform cells.",
  "study_system": "mouse somatosensory cortex; immunohistochemistry + 5HT3aR-BAC reporter",
  "evidence_refs": [
    {
      "ref": "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
    }
  ],
  "section_title": "Molecular Identity and Transcriptomic Taxonomy",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Triple-marker (PV/SST/5HT3aR) cytometric scheme accounts for ~100% mouse S1 GABAergic interneurons; 5HT3aR group ~30% of total INs; ~40% of 5HT3aR group express VIP; PV/SST/VIP non-overlapping major classes.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-02-classification",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}