Gamma frequency entrainment attenuates amyloid load and modifies microglia

Details

scope: Alzheimer's disease / neurodegeneration
claim_text: Gamma frequency entrainment attenuates amyloid load and modifies microglia
section_id: section_11_evidence_package
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_11_evidence_package.json
effect_size: Changes in gamma oscillations (20-50 Hz) have been observed in several neurological disorders
review_repo: ComputationalReviewPV
section_ref: wiki_page:computationalreviewpv-11
source_kind: review_finding
source_path: evidence/section_11_evidence_package.json
source_span: Changes in gamma oscillations (20-50 Hz) have been observed in several neurological disorders.
study_system: Alzheimer's disease / neurodegeneration
section_title: Species Translation, Human Data, and Disease Models
evidence_summary: Study on PV interneurons in Alzheimer's/neurodegeneration
review_bundle_ref: analysis_bundle:ab-e6261c8263e7
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-e6261c8263e7
source_artifact_ref: wiki_page:computationalreviewpv-11
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_11_evidence_package.json
commit_sha: df9fc7e8d455b084152c9d713558dae0013cef21
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1038/nature20587",
  "claim": "Gamma frequency entrainment attenuates amyloid load and modifies microglia",
  "evidence": "Study on PV interneurons in Alzheimer's/neurodegeneration",
  "effect_size": "Changes in gamma oscillations (20-50 Hz) have been observed in several neurological disorders",
  "text_access": "abstract_only",
  "study_system": "Alzheimer's disease / neurodegeneration",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Changes in gamma oscillations (20-50 Hz) have been observed in several neurological disorders.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Changes in gamma oscillations (20-50 Hz) have been observed in several neurological disorders."
}

source_refs

[
  "paper:paper-27dffa8cbc0a"
]

evidence_refs

[
  {
    "ref": "paper:paper-27dffa8cbc0a"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Gamma frequency entrainment attenuates amyloid load and modifies microglia

Details

Replication

Discussion