- claim_text
PV basket cells evoke greater inhibition in deep-layer CA1 pyramidal cells than superficial, and analysis of reciprocal connectivity reveals bias in target selection by both excitatory and inhibitory local connections, demonstrating heterogeneous PVBC-PC microcircuits.
- raw_fields
{
"n": 0,
"doi": "10.1016/j.neuron.2014.03.034",
"claim": "PV basket cells evoke greater inhibition in deep-layer CA1 pyramidal cells than superficial, and analysis of reciprocal connectivity reveals bias in target selection by both excitatory and inhibitory local connections, demonstrating heterogeneous PVBC-PC microcircuits.",
"evidence": "Paired recordings in vitro, 2-photon Ca2+ imaging in vivo, and computational modeling showed PVBCs further segregate among deep PCs by projection target.",
"effect_size": "greater PVBC inhibition in deep vs superficial CA1 PCs; preferential innervation of amygdala-projecting PCs",
"text_access": "fulltext",
"study_system": "mouse hippocampal CA1",
"replication_status": "replication_unknown",
"claim_source_sentence": "We found that parvalbumin-expressing basket cells (PVBCs) evoked greater inhibition in CA1 PCs located in the deep compared to superficial layer of stratum pyramidale.",
"replication_evidence_dois": [],
"effect_size_source_sentence": "PVBCs further segregated among deep PCs, preferentially innervating the amygdala-projecting PCs but receiving preferential excitation from the prefrontal cortex-projecting PCs."
}- source_refs
[
"paper:paper-722a8aa86ab1"
]
- evidence_refs
[
{
"ref": "paper:paper-722a8aa86ab1"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}