Details

scope
whole adult mouse brain
claim_text
Transcription factors are major determinants of cell type classification in adult mouse brain, with a combinatorial TF code defining cell types including PV interneurons across all brain regions.
section_id
section_02_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
effect_size
combinatorial TF code defines cell types across all brain regions
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-02
source_kind
review_finding
source_path
evidence/section_02_evidence_package.json
source_span
We found that transcription factors are major determinants of cell type classification in the adult mouse brain and identified a combinatorial transcription factor code that defines cell types across all parts of the brain.
study_system
whole adult mouse brain
section_title
Molecular Identity and Transcriptomic Taxonomy
evidence_summary
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-02
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
raw_fields
{
  "n": 7000000,
  "doi": "10.1101/2023.03.06.531121",
  "claim": "Transcription factors are major determinants of cell type classification in adult mouse brain, with a combinatorial TF code defining cell types including PV interneurons across all brain regions.",
  "evidence": "",
  "effect_size": "combinatorial TF code defines cell types across all brain regions",
  "text_access": "abstract_only",
  "study_system": "whole adult mouse brain",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "We found that transcription factors are major determinants of cell type classification in the adult mouse brain and identified a combinatorial transcription factor code that defines cell types across all parts of the brain.",
  "replication_evidence_dois": [
    "10.1038/s41586-023-06812-z"
  ],
  "effect_size_source_sentence": "We found that transcription factors are major determinants of cell type classification in the adult mouse brain and identified a combinatorial transcription factor code that defines cell types across all parts of the brain."
}
source_refs
[
  "paper:paper-d633019640ee"
]
evidence_refs
[
  {
    "ref": "paper:paper-d633019640ee"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.