Details
- scope
- mouse primary visual cortex (V1), in vivo 2-photon + serial EM
- claim_text
- Combined functional imaging + serial-section electron microscopy of mouse V1 reveals that ~half (49%) of synapses from L2/3 pyramidal neurons in the EM-imaged volume contact excitatory dendrites and ~half (51%) contact inhibitory dendrites.
- section_id
- section_01
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
- effect_size
- 49% excitatory / 51% inhibitory postsynaptic targets
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-01-introduction
- source_kind
- review_finding
- source_path
- evidence/section_01_evidence_package.json
- source_span
- Of 245 synapses originating from 10 functionally characterized pyramidal neurons that made synapses in the EM-imaged volume, 125 (51%) were onto inhibitory dendrites and 120 (49%) onto excitatory dendrites.
- study_system
- mouse primary visual cortex (V1), in vivo 2-photon + serial EM
- section_title
- 1. Introduction — what "excitatory recurrence" means operationally in mouse cortex, and why isolating it from inhibition and from clinical framings is a defensible analytic move for basic-research synthesis
- evidence_summary
- Functional two-photon calcium imaging of orientation tuning in mouse V1 followed by serial-section EM reconstruction of the same tissue volume.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-01-introduction
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
- raw_fields
{ "n": "245 synapses from 10 pyramidal neurons", "doi": "10.1038/nature09802", "claim": "Combined functional imaging + serial-section electron microscopy of mouse V1 reveals that ~half (49%) of synapses from L2/3 pyramidal neurons in the EM-imaged volume contact excitatory dendrites and ~half (51%) contact inhibitory dendrites.", "cite_key": "Bock2011", "evidence": "Functional two-photon calcium imaging of orientation tuning in mouse V1 followed by serial-section EM reconstruction of the same tissue volume.", "effect_size": "49% excitatory / 51% inhibitory postsynaptic targets", "text_access": "fulltext", "study_system": "mouse primary visual cortex (V1), in vivo 2-photon + serial EM", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "Of 245 synapses originating from 10 functionally characterized pyramidal neurons that made synapses in the EM-imaged volume, 125 (51%) were onto inhibitory dendrites and 120 (49%) onto excitatory dendrites.", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": "Of 245 synapses originating from 10 functionally characterized pyramidal neurons that made synapses in the EM-imaged volume, 125 (51%) were onto inhibitory dendrites and 120 (49%) onto excitatory dendrites." }- source_refs
[ "paper:paper-a80aa5d68f45" ]
- evidence_refs
[ { "ref": "paper:paper-a80aa5d68f45" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }