- claim_text
VIP interneurons in mouse motor cortex undergo spike-timing-dependent plasticity (STDP) at I→I synapses onto Martinotti and basket cells; these plasticity rules are synapse-type-specific and contribute to disinhibitory circuit reconfiguration during motor learning.
- raw_fields
{
"n": null,
"doi": "10.3389/fncel.2024.1389094",
"claim": "VIP interneurons in mouse motor cortex undergo spike-timing-dependent plasticity (STDP) at I→I synapses onto Martinotti and basket cells; these plasticity rules are synapse-type-specific and contribute to disinhibitory circuit reconfiguration during motor learning.",
"title": null,
"cite_key": "Mcfarlan2024a",
"evidence": "Patch-clamp pairing protocols + computational modeling in mouse M1 slice.",
"effect_size": null,
"text_access": "fulltext",
"study_system": "mouse M1; ex vivo patch + model",
"_source_cluster": "cluster_05_synaptic_connectivity",
"replication_status": "single-study",
"_source_cluster_index": 54,
"claim_source_sentence": "The plasticity of inhibitory interneurons (INs) plays an important role in the organization and maintenance of cortical microcircuits.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-c141a5bf864f"
]
- evidence_refs
[
{
"ref": "paper:paper-c141a5bf864f"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}