- raw_fields
{
"n": null,
"doi": "10.1038/s41467-020-15352-3",
"claim": "GPe orchestrates abnormal beta-band network dynamics in a 6-OHDA mouse model of Parkinsonism, with prototypic neurons leading pathological synchrony.",
"cite_key": "Crompe2020",
"evidence": "Multielectrode recording and cell-type optogenetics in 6-OHDA mouse GPe and STN.",
"effect_size": "see source sentence",
"text_access": "fulltext",
"study_system": "mouse (6-OHDA; in vivo multielectrode + opto)",
"source_cluster_id": "cluster_02",
"replication_status": "replication_unknown",
"claim_source_sentence": "Combining STN-ChR2 β -patterning with unit activity recordings of the two main population of GP neurons (i.e., the prototypic and arkypallidal cells) also reveal that synthetic β -oscillations could propagate to GP neurons and cause a significant increase in the temporal coupling (measured through coherence analysis) between cortex and the two populations of GP neurons (Supplementary Fig.",
"replication_evidence_dois": [],
"effect_size_source_sentence": "The efficacy of STN opto-inhibition was verified for each animal using opto-electrode mapping and the animals that did not reach satisfactory level of STN inhibition (i.e., >60%) were excluded from further analysis (see ‘Methods’)."
}- source_refs
[
"paper:paper-2d3f0b7ed612"
]
- source_span
Combining STN-ChR2 β -patterning with unit activity recordings of the two main population of GP neurons (i.e., the prototypic and arkypallidal cells) also reveal that synthetic β -oscillations could propagate to GP neurons and cause a significant increase in the temporal coupling (measured through coherence analysis) between cortex and the two populations of GP neurons (Supplementary Fig.
- evidence_refs
[
{
"ref": "paper:paper-2d3f0b7ed612"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}