Details

scope
rat striatum, 6-OHDA lesion model
claim_text
Unilateral nigrostriatal lesion decreases the response of fast-spiking interneurons to cortical input
section_id
section_06_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-06
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
source_span
5-Hydroxytryptamine(1A) (5-HT(1A)) receptors are expressed in the prefrontal cortical interneurons. Among these interneurons, calcium-binding protein parvalbumin (PV)-positive fast spiking (FS) intern
study_system
rat striatum, 6-OHDA lesion model
section_title
Synaptic Physiology: Input Specificity, Output Targeting, and Short-Term Dynamics
evidence_summary
Dopamine depletion reduces excitatory drive to fast-spiking interneurons in striatum
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-06
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1016/j.neuint.2011.05.004",
  "claim": "Unilateral nigrostriatal lesion decreases the response of fast-spiking interneurons to cortical input",
  "evidence": "Dopamine depletion reduces excitatory drive to fast-spiking interneurons in striatum",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "rat striatum, 6-OHDA lesion model",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "5-Hydroxytryptamine(1A) (5-HT(1A)) receptors are expressed in the prefrontal cortical interneurons. Among these interneurons, calcium-binding protein parvalbumin (PV)-positive fast spiking (FS) intern",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-4c3fd7115cf6"
]
evidence_refs
[
  {
    "ref": "paper:paper-4c3fd7115cf6"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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