Version history

{
  "scope": "rodent cortex (review/anatomical)",
  "claim_text": "CR+/VIP+ bipolar interneurons receive predominantly depressing excitatory inputs but produce facilitating outputs onto SOM+ Martinotti cells; the group III metabotropic receptor mGluR7 is presynaptically localized at CR+/VIP+→SOM+ synapses, providing glutamatergic regulation of the disinhibitory motif.",
  "raw_fields": {
    "n": null,
    "doi": "10.3389/fnana.2014.00052",
    "claim": "CR+/VIP+ bipolar interneurons receive predominantly depressing excitatory inputs but produce facilitating outputs onto SOM+ Martinotti cells; the group III metabotropic receptor mGluR7 is presynaptically localized at CR+/VIP+→SOM+ synapses, providing glutamatergic regulation of the disinhibitory motif.",
    "title": null,
    "cite_key": "Cauli2014",
    "evidence": "Anatomical and electrophysiological review/synthesis of CR/VIP and CR/SOM interneurons across rodent cortex.",
    "effect_size": "Qualitative: opposite STP polarity for inputs vs outputs of VIP cells; mGluR7 presynaptic on VIP→SOM synapses.",
    "text_access": "fulltext",
    "study_system": "rodent cortex (review/anatomical)",
    "_source_cluster": "cluster_05_synaptic_connectivity",
    "replication_status": "replicated",
    "_source_cluster_index": 21,
    "claim_source_sentence": "Interestingly, it appears that inputs to CR+/VIP+ (BCR) neurons are mainly depressing (Porter et al., ; Rozov et al., ), whereas all their outputs are facilitating and, vice versa, for CR+/SOM+ (MCR) neurons inputs are often facilitating whereas their outputs show a target cell t",
    "replication_evidence_dois": [
      "10.1016/j.neuron.2016.02.037"
    ],
    "effect_size_source_sentence": "The group III metabotropic receptor mGluR7 expressed by CR+/VIP+ bipolar neurons (Cauli et al., ) is presynaptically localized onto synapses targeting SOM+ interneurons which suggests a glutamatergic control of disinhibition (Dalezios et al., )."
  },
  "section_id": "section_06",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json",
  "effect_size": "Qualitative: opposite STP polarity for inputs vs outputs of VIP cells; mGluR7 presynaptic on VIP→SOM synapses.",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-06-synaptic-properties",
  "source_kind": "review_finding",
  "source_path": "evidence/section_06_evidence_package.json",
  "source_refs": [
    "paper:paper-ba54efae783d"
  ],
  "source_span": "Interestingly, it appears that inputs to CR+/VIP+ (BCR) neurons are mainly depressing (Porter et al., ; Rozov et al., ), whereas all their outputs are facilitating and, vice versa, for CR+/SOM+ (MCR) neurons inputs are often facilitating whereas their outputs show a target cell t",
  "study_system": "rodent cortex (review/anatomical)",
  "evidence_refs": [
    {
      "ref": "paper:paper-ba54efae783d"
    }
  ],
  "section_title": "Synaptic Properties and Connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Anatomical and electrophysiological review/synthesis of CR/VIP and CR/SOM interneurons across rodent cortex.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-06-synaptic-properties",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}