Details
- scope
- human MRI/PET model synthesis
- claim_text
- Schizophrenia symptoms are proposed to arise from a disruption in cortical-subcortical-cerebellar circuitry connecting prefrontal regions, thalamic nuclei, and cerebellum, producing a cognitive dysmetria.
- section_id
- section_07
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-07
- source_kind
- review_finding
- source_path
- evidence/section_07_evidence_package.json
- source_span
- A disruption in this circuitry produces "cognitive dysmetria," difficulty in prioritizing, processing, coordinating, and responding to information.
- study_system
- human MRI/PET model synthesis
- section_title
- Parallel Loop Channels: Motor, Limbic, Associative, and Beyond the Classic Three
- evidence_summary
- Integrative model based on MRI and PET data implicates connectivity among prefrontal cortex, thalamus, and cerebellum, framing schizophrenia symptoms as breakdown in parallel distributed CBGTC dynamic circuits.
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-07
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1093/oxfordjournals.schbul.a033321", "claim": "Schizophrenia symptoms are proposed to arise from a disruption in cortical-subcortical-cerebellar circuitry connecting prefrontal regions, thalamic nuclei, and cerebellum, producing a cognitive dysmetria.", "cite_key": "Andreasen1998", "evidence": "Integrative model based on MRI and PET data implicates connectivity among prefrontal cortex, thalamus, and cerebellum, framing schizophrenia symptoms as breakdown in parallel distributed CBGTC dynamic circuits.", "effect_size": null, "text_access": "abstract_only", "study_system": "human MRI/PET model synthesis", "source_cluster_id": "cluster_06", "replication_status": "independently_replicated", "claim_source_sentence": "A disruption in this circuitry produces \"cognitive dysmetria,\" difficulty in prioritizing, processing, coordinating, and responding to information.", "replication_evidence_dois": [ "10.3389/fnsys.2016.00104" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-d522c8a49d59" ]
- evidence_refs
[ { "ref": "paper:paper-d522c8a49d59" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }