Version history

{
  "scope": "mouse, MGE dorsal/ventral progenitors (review)",
  "claim_text": "Within the medial ganglionic eminence (MGE), dorsal vs. ventral progenitor regions bias toward different MGE-derived interneuron subtypes — somatostatin-expressing interneurons preferentially originate from dorsal MGE while parvalbumin-expressing interneurons preferentially originate from ventral MGE.",
  "raw_fields": {
    "n": null,
    "doi": "10.1002/dneu.20853",
    "claim": "Within the medial ganglionic eminence (MGE), dorsal vs. ventral progenitor regions bias toward different MGE-derived interneuron subtypes — somatostatin-expressing interneurons preferentially originate from dorsal MGE while parvalbumin-expressing interneurons preferentially originate from ventral MGE.",
    "title": null,
    "cite_key": "Rudy2011",
    "evidence": "Compendium of fate-mapping/transplantation studies (Flames 2007; Fogarty 2007; Wonders 2008) probing dorsal/ventral MGE-restricted progenitor pools.",
    "effect_size": "Dorsal MGE → SST-biased; ventral MGE → PV-biased",
    "figure_data": [],
    "text_access": "fulltext",
    "study_system": "mouse, MGE dorsal/ventral progenitors (review)",
    "_source_cluster": "cluster_02_development_lineage",
    "replication_status": "review",
    "_source_cluster_index": 113,
    "claim_source_sentence": "It has also been reported that different regions of the MGE give rise to different subtypes, with progenitors giving rise to SST and PV being biased to dorsal versus ventral MGE, respectively ( Flames et al., 2007 ; Fogarty et al., 2007 ; Wonders et al., 2008 ).",
    "replication_evidence_dois": [
      "10.1523/jneurosci.1629-07.2007"
    ],
    "effect_size_source_sentence": "It has also been reported that different regions of the MGE give rise to different subtypes, with progenitors giving rise to SST and PV being biased to dorsal versus ventral MGE, respectively ( Flames et al., 2007 ; Fogarty et al., 2007 ; Wonders et al., 2008 )."
  },
  "section_id": "section_03",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "effect_size": "Dorsal MGE → SST-biased; ventral MGE → PV-biased",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-03-development",
  "source_kind": "review_finding",
  "source_path": "evidence/section_03_evidence_package.json",
  "source_refs": [
    "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
  ],
  "source_span": "It has also been reported that different regions of the MGE give rise to different subtypes, with progenitors giving rise to SST and PV being biased to dorsal versus ventral MGE, respectively ( Flames et al., 2007 ; Fogarty et al., 2007 ; Wonders et al., 2008 ).",
  "study_system": "mouse, MGE dorsal/ventral progenitors (review)",
  "evidence_refs": [
    {
      "ref": "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
    }
  ],
  "section_title": "Developmental Origins and Postnatal Maturation",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Compendium of fate-mapping/transplantation studies (Flames 2007; Fogarty 2007; Wonders 2008) probing dorsal/ventral MGE-restricted progenitor pools.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "review",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-03-development",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}