In mouse posterior parietal cortex during a virtual-reality delayed match-to-sa…

In mouse posterior parietal cortex during a virtual-reality delayed match-to-sample task, neurons projecting to the same downstream target form structured pairwise correlations — combining information-limiting and information-enhancing motifs — that enhance choice information beyond what is conveyed by pairwise interactions and are absent from nearby unlabelled populations.

{
  "n": 0,
  "doi": "10.1038/s41593-025-02095-x",
  "claim": "In mouse posterior parietal cortex during a virtual-reality delayed match-to-sample task, neurons projecting to the same downstream target form structured pairwise correlations — combining information-limiting and information-enhancing motifs — that enhance choice information beyond what is conveyed by pairwise interactions and are absent from nearby unlabelled populations.",
  "cite_key": "Safaai2025",
  "evidence": "",
  "effect_size": "",
  "text_access": "abstract_only",
  "study_system": "mouse PPC; calcium imaging + retrograde labelling during delayed match-to-sample VR task",
  "argument_role": "supporting",
  "replication_status": "single_lab",
  "claim_source_sentence": "We found that neurons projecting to the same area have elevated pairwise activity correlations.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "These correlations are structured as information-limiting and information-enhancing motifs that shape interaction networks and collectively enhance information about the mouse's choice beyond what is contributed by pairwise interactions."
}

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