Details

scope
mouse visual, somatosensory, motor cortex; two-population ISN model
claim_text
Inhibition stabilization is a widespread property of cortical networks across visual, somatosensory, and motor cortex
section_id
section_12_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_12_evidence_package.json
effect_size
ISN effects detected without sensory stimulation and during light anesthesia
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-12
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
source_span
We find clear evidence for ISN operation in mouse visual, somatosensory, and motor cortex. Simple two-population ISN models describe the data well and let us quantify coupling strength.
study_system
mouse visual, somatosensory, motor cortex; two-population ISN model
section_title
Computational Models of PV Circuit Function
evidence_summary
Optogenetic perturbation experiments matched to two-population ISN models in multiple cortical areas
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-12
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_12_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.7554/elife.54875",
  "claim": "Inhibition stabilization is a widespread property of cortical networks across visual, somatosensory, and motor cortex",
  "evidence": "Optogenetic perturbation experiments matched to two-population ISN models in multiple cortical areas",
  "effect_size": "ISN effects detected without sensory stimulation and during light anesthesia",
  "text_access": "fulltext",
  "study_system": "mouse visual, somatosensory, motor cortex; two-population ISN model",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We find clear evidence for ISN operation in mouse visual, somatosensory, and motor cortex. Simple two-population ISN models describe the data well and let us quantify coupling strength.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Although some models predict a non-ISN to ISN transition with increasingly strong sensory stimuli, we find ISN effects without sensory stimulation and even during light anesthesia."
}
source_refs
[
  "paper:paper-d6edd2b57842"
]
evidence_refs
[
  {
    "ref": "paper:paper-d6edd2b57842"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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