Version history

{
  "scope": "mouse; visual cortex; Annual review of neuroscience",
  "claim_text": "A working hypothesis, based on theoretical and experimental evidence, that SM results from feedforward, horizontal, and feedback interactions with local recurrent connections, via synaptic mechanisms…",
  "raw_fields": {
    "n": null,
    "doi": "10.1146/annurev-neuro-072116-031418",
    "claim": "A working hypothesis, based on theoretical and experimental evidence, that SM results from feedforward, horizontal, and feedback interactions with local recurrent connections, via synaptic mechanisms…",
    "cite_key": "Angelucci2017",
    "evidence": "Surround modulation (SM) is a fundamental property of sensory neurons in many species and sensory modalities. SM is the ability of stimuli in the surround of a neuron's receptive field (RF) to modulate (typically suppress) the neuron's response to stimuli simultaneously presented inside the RF, a property thought to underlie optimal coding of sensory information and important perceptual functions. Understanding the circuit and mechanisms for SM can reveal fundamental principles of computations i...",
    "effect_size": "These authors found that at low light intensities, V2 feedback inactivation caused a shift of the size-tuning peak toward larger stimuli, i.e. an increase in RF size, which, in about 50% of the cells was accompanied by an increase in the height of the peak ().",
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    "study_system": "mouse; visual cortex; Annual review of neuroscience",
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    "claim_source_sentence": "Here we present a working hypothesis, based on theoretical and experimental evidence, that SM results from feedforward, horizontal, and feedback interactions with local recurrent connections, via synaptic mechanisms involving both increased inhibition and reduced recurrent excitation.",
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    "replication_evidence_dois": [],
    "claim_rewritten_from_source": true,
    "effect_size_source_sentence": "These authors found that at low light intensities, V2 feedback inactivation caused a shift of the size-tuning peak toward larger stimuli, i.e. an increase in RF size, which, in about 50% of the cells was accompanied by an increase in the height of the peak ()."
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  "section_id": "section_09",
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  "effect_size": "These authors found that at low light intensities, V2 feedback inactivation caused a shift of the size-tuning peak toward larger stimuli, i.e. an increase in RF size, which, in about 50% of the cells was accompanied by an increase in the height of the peak ().",
  "review_repo": "ComputationalReviewRecurrence",
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  "source_span": "Here we present a working hypothesis, based on theoretical and experimental evidence, that SM results from feedforward, horizontal, and feedback interactions with local recurrent connections, via synaptic mechanisms involving both increased inhibition and reduced recurrent excitation.",
  "study_system": "mouse; visual cortex; Annual review of neuroscience",
  "evidence_refs": [
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  "section_title": "9. Physiological signature I — recurrent amplification of weak inputs in mouse cortex; balanced-amplification regimes; ISN operation",
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    "notes": [
      "Local review repositories are read-only inputs.",
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  "evidence_summary": "Surround modulation (SM) is a fundamental property of sensory neurons in many species and sensory modalities. SM is the ability of stimuli in the surround of a neuron's receptive field (RF) to modulate (typically suppress) the neuron's response to stimuli simultaneously presented inside the RF, a property thought to underlie optimal coding of sensory information and important perceptual functions. Understanding the circuit and mechanisms for SM can reveal fundamental principles of computations i...",
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  "replication_status": "single_study",
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