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- Live5/17/2026, 4:35:28 PM
a89e32832537Content snapshot
{ "scope": "awake mouse V1; two-photon optogenetic ensemble imprinting with chronic Ca imaging", "claim_text": "Repetitive two-photon optogenetic co-activation in awake mouse V1 imprints recurrent neuronal ensembles that recur spontaneously, can be recalled by single-cell stimulation, and persist across days, d", "raw_fields": { "n": 0, "doi": "10.1126/science.aaf7560", "claim": "Repetitive two-photon optogenetic co-activation in awake mouse V1 imprints recurrent neuronal ensembles that recur spontaneously, can be recalled by single-cell stimulation, and persist across days, d", "cite_key": "CarrilloReid2016", "evidence": "Two-photon optogenetic patterned co-activation of small V1 populations in awake mice, followed by spontaneous/evoked imaging across consecutive days.", "effect_size": "Imprinted ensembles persist across days; single-cell stimulation recalls full ensemble (pattern completion)", "text_access": "abstract_only", "study_system": "awake mouse V1; two-photon optogenetic ensemble imprinting with chronic Ca imaging", "argument_role": "supporting", "original_section": "section_05", "replication_status": "single_study", "claim_source_sentence": "[via section_11] Here we report that repetitive activation with two-photon optogenetics of neuronal populations from ensembles in the visual cortex of awake mice builds neuronal ensembles that recur spontaneously after being imprinted and do not disrupt preexisting ones.", "conflict_context_borrow": true, "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "Moreover, imprinted ensembles can be recalled by single- cell stimulation and remain coactive on consecutive days." }, "section_id": "section_11", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json", "effect_size": "Imprinted ensembles persist across days; single-cell stimulation recalls full ensemble (pattern completion)", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-11-pattern-completion", "source_kind": "review_finding", "source_path": "evidence/section_11_evidence_package.json", "source_refs": [ "paper:paper-c02ea00d7195" ], "source_span": "[via section_11] Here we report that repetitive activation with two-photon optogenetics of neuronal populations from ensembles in the visual cortex of awake mice builds neuronal ensembles that recur spontaneously after being imprinted and do not disrupt preexisting ones.", "study_system": "awake mouse V1; two-photon optogenetic ensemble imprinting with chronic Ca imaging", "evidence_refs": [ { "ref": "paper:paper-c02ea00d7195" } ], "section_title": "11. Physiological signature III — pattern completion, replay, and sequence generation as recurrent-circuit read-outs in mouse cortex", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Two-photon optogenetic patterned co-activation of small V1 populations in awake mice, followed by spontaneous/evoked imaging across consecutive days.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "single_study", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-11-pattern-completion", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }