- claim_text
An excitatory projection from presubiculum and retrosplenial cortex to anterodorsal thalamic reticular nucleus (TRN) modulates head-direction tuning in anterior thalamus: chemogenetic anterodorsal TRN inhibition broadens HD-cell tuning and shifts navigation strategies, identifying a cortical input to the TRN that sharpens HD signals supporting attractor-like compass coding.
- raw_fields
{
"n": 0,
"doi": "10.1016/j.celrep.2020.107747",
"claim": "An excitatory projection from presubiculum and retrosplenial cortex to anterodorsal thalamic reticular nucleus (TRN) modulates head-direction tuning in anterior thalamus: chemogenetic anterodorsal TRN inhibition broadens HD-cell tuning and shifts navigation strategies, identifying a cortical input to the TRN that sharpens HD signals supporting attractor-like compass coding.",
"cite_key": "Vantomme2020",
"evidence": "",
"effect_size": "",
"text_access": "abstract_only",
"study_system": "mouse PreS-RSC-anterodorsal TRN-anterior thalamus circuit; in-vitro + in-vivo recordings, chemogenetic inhibition",
"argument_role": "supporting",
"replication_status": "single_lab",
"claim_source_sentence": "In vivo, chemogenetic anterodorsal TRN inhibition modulates PreS/RSC-induced anterior thalamic firing dynamics, broadens the tuning of thalamic HD cells, and leads to preferential use of allo- over egocentric search strategies in the Morris water maze.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-9cf9953cb0b4"
]
- source_span
In vivo, chemogenetic anterodorsal TRN inhibition modulates PreS/RSC-induced anterior thalamic firing dynamics, broadens the tuning of thalamic HD cells, and leads to preferential use of allo- over egocentric search strategies in the Morris water maze.
- evidence_refs
[
{
"ref": "paper:paper-9cf9953cb0b4"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}