Details

scope
biophysical spiking model of primate prefrontal cortex (Compte–Brunel–Wang–Wang)
claim_text
Continuous bump-attractor model of spatial working memory requires that recurrent excitation be NMDA-dominated and that net recurrent interactions be inhibition-dominated.
section_id
section_13
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_13_evidence_package.json
effect_size
qualitative
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-13-attractor-network-models
source_kind
review_finding
source_path
evidence/section_13_evidence_package.json
source_span
To observe stable spontaneous and persistent activity, we find that recurrent synaptic excitation should be primarily mediated by NMDA receptors, and that overall recurrent synaptic interactions should be dominated by inhibition.
study_system
biophysical spiking model of primate prefrontal cortex (Compte–Brunel–Wang–Wang)
section_title
13. Attractor-network models — Hopfield, ring, line, bump; what each model requires of the cortical E→E matrix and what the mouse empirical record provides
evidence_summary
Biophysical spiking-network model of a prefrontal cortical column with structured E→E and E→I connectivity; constraints derived analytically and verified by simulation.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-13-attractor-network-models
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_13_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1093/cercor/10.9.910",
  "claim": "Continuous bump-attractor model of spatial working memory requires that recurrent excitation be NMDA-dominated and that net recurrent interactions be inhibition-dominated.",
  "cite_key": "Compte2000",
  "evidence": "Biophysical spiking-network model of a prefrontal cortical column with structured E→E and E→I connectivity; constraints derived analytically and verified by simulation.",
  "effect_size": "qualitative",
  "text_access": "abstract_only",
  "study_system": "biophysical spiking model of primate prefrontal cortex (Compte–Brunel–Wang–Wang)",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "To observe stable spontaneous and persistent activity, we find that recurrent synaptic excitation should be primarily mediated by NMDA receptors, and that overall recurrent synaptic interactions should be dominated by inhibition.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1038/nn.3645",
    "10.1073/pnas.0807122105"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-6244370d231f"
]
evidence_refs
[
  {
    "ref": "paper:paper-6244370d231f"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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