Details
- scope
- mouse, V1, optogenetic SOM activation
- claim_text
- SOM+ interneuron activation suppresses PV+ cell spiking at least twice as potently as pyramidal cell spiking during visual stimulation
- section_id
- section_08_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
- effect_size
- at least 2x more potent suppression of PV than pyramidal cells
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-08
- source_kind
- review_finding
- source_path
- evidence/section_08_evidence_package.json
- source_span
- SOM(+) interneuron activation suppresses PV(+) cell spiking at least twice as potently as pyramidal cell spiking during visual stimulation
- study_system
- mouse, V1, optogenetic SOM activation
- section_title
- In Vivo Dynamics and Behavioural Correlates
- evidence_summary
- SOM inhibition of PV cells unmasks orientation tuning in PV cells by suppressing untuned input; competitive inhibition between interneuron types reconfigures inhibition along somatodendritic axis
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-08
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1523/JNEUROSCI.2624-13.2013", "claim": "SOM+ interneuron activation suppresses PV+ cell spiking at least twice as potently as pyramidal cell spiking during visual stimulation", "evidence": "SOM inhibition of PV cells unmasks orientation tuning in PV cells by suppressing untuned input; competitive inhibition between interneuron types reconfigures inhibition along somatodendritic axis", "effect_size": "at least 2x more potent suppression of PV than pyramidal cells", "text_access": "fulltext", "study_system": "mouse, V1, optogenetic SOM activation", "replication_status": "independently_replicated", "claim_source_sentence": "SOM(+) interneuron activation suppresses PV(+) cell spiking at least twice as potently as pyramidal cell spiking during visual stimulation", "replication_evidence_dois": [ "10.1038/nature13128" ], "effect_size_source_sentence": "SOM(+) interneuron activation suppresses PV(+) cell spiking at least twice as potently as pyramidal cell spiking during visual stimulation" }- source_refs
[ "paper:paper-1cd7cf967531" ]
- evidence_refs
[ { "ref": "paper:paper-1cd7cf967531" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }