Details

scope
human prefrontal cortex, 20 matched pairs schizophrenia vs control
claim_text
CB+ chandelier cell cartridge density is 2.7-fold higher in layer 2 of schizophrenia subjects, suggesting blunted developmental pruning
section_id
section_04_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_04_evidence_package.json
effect_size
2.7-fold increase in CB+ cartridge density in schizophrenia layer 2
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-04
source_kind
review_finding
source_path
evidence/section_04_evidence_package.json
source_span
The mean density of vGAT+/CB+ cartridges was 2.7-fold higher, exclusively in layer 2 of schizophrenia subjects, whereas the density of vGAT+/CB- cartridges did not differ between subject groups.
study_system
human prefrontal cortex, 20 matched pairs schizophrenia vs control
section_title
Morphological Diversity: Basket Cells, Chandelier Cells, and Beyond
evidence_summary
CB+ chandelier cell cartridge density is 2.7-fold higher in layer 2 of schizophrenia subjects, suggesting blunted developmental pruning
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-04
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_04_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
raw_fields
{
  "n": 20,
  "doi": "10.1016/j.biopsych.2016.09.018",
  "claim": "CB+ chandelier cell cartridge density is 2.7-fold higher in layer 2 of schizophrenia subjects, suggesting blunted developmental pruning",
  "evidence": "CB+ chandelier cell cartridge density is 2.7-fold higher in layer 2 of schizophrenia subjects, suggesting blunted developmental pruning",
  "effect_size": "2.7-fold increase in CB+ cartridge density in schizophrenia layer 2",
  "text_access": "fulltext",
  "study_system": "human prefrontal cortex, 20 matched pairs schizophrenia vs control",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "The mean density of vGAT+/CB+ cartridges was 2.7-fold higher, exclusively in layer 2 of schizophrenia subjects, whereas the density of vGAT+/CB- cartridges did not differ between subject groups.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "The mean density of vGAT+/CB+ cartridges was 2.7-fold higher, exclusively in layer 2 of schizophrenia subjects."
}
source_refs
[
  "paper:paper-088fa528776a"
]
evidence_refs
[
  {
    "ref": "paper:paper-088fa528776a"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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