- raw_fields
{
"n": 0,
"doi": "10.7554/elife.90826",
"claim": "The reuniens nucleus of the thalamus facilitates hippocampo-cortical dialogue during sleep",
"cite_key": "Basha2025",
"evidence": "Memory consolidation during sleep depends on the interregional coupling of slow waves, spindles, and sharp wave-ripples (SWRs), across the cortex, thalamus, and hippocampus. The reuniens nucleus of the thalamus, linking the medial prefrontal cortex (mPFC) and the hippocampus, may facilitate interregional coupling during sleep. To test this hypothesis, we used intracellular, extracellular unit and ",
"effect_size": null,
"text_access": "fulltext",
"study_system": "rat, cat, nucleus reuniens, PFC",
"source_cluster_id": "cluster_05",
"replication_status": "replication_unknown",
"claim_source_sentence": "Using in vivo intracellular recordings, computational modelling, and spike/local field potential (LFP) recordings, we demonstrate that reuniens is driven by hippocampal oscillations during sleep and that it elicits fast, consistent synaptic responses in mPFC.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-1a11bd2e94eb"
]
- source_span
Using in vivo intracellular recordings, computational modelling, and spike/local field potential (LFP) recordings, we demonstrate that reuniens is driven by hippocampal oscillations during sleep and that it elicits fast, consistent synaptic responses in mPFC.
- evidence_refs
[
{
"ref": "paper:paper-1a11bd2e94eb"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}- evidence_summary
Memory consolidation during sleep depends on the interregional coupling of slow waves, spindles, and sharp wave-ripples (SWRs), across the cortex, thalamus, and hippocampus. The reuniens nucleus of the thalamus, linking the medial prefrontal cortex (mPFC) and the hippocampus, may facilitate interregional coupling during sleep. To test this hypothesis, we used intracellular, extracellular unit and