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- Live5/17/2026, 4:35:28 PM
6d9594d46735Content snapshot
{ "scope": "mouse ALM; electrophysiology + targeted optogenetic photostimulation during memory-guided directional licking", "claim_text": "In mouse ALM during a memory-guided movement task, choice selectivity grows as it propagates through a sequence of activity-space directions: early directions carry little selectivity but large predicted behavioural influence, late directions carry large selectivity and little influence, consistent with a feedforward-amplification motif in recurrent networks rather than a stable attractor; targeted photostimulation triggered the predicted sequential propagation and behavioural biases.", "raw_fields": { "n": 0, "doi": "10.1101/2023.08.04.552026", "claim": "In mouse ALM during a memory-guided movement task, choice selectivity grows as it propagates through a sequence of activity-space directions: early directions carry little selectivity but large predicted behavioural influence, late directions carry large selectivity and little influence, consistent with a feedforward-amplification motif in recurrent networks rather than a stable attractor; targeted photostimulation triggered the predicted sequential propagation and behavioural biases.", "cite_key": "Daie2023", "evidence": "", "effect_size": "", "text_access": "abstract_only", "study_system": "mouse ALM; electrophysiology + targeted optogenetic photostimulation during memory-guided directional licking", "argument_role": "supporting", "replication_status": "single_lab", "claim_source_sentence": "Choice selectivity grew as it flowed through a sequence of directions in activity space.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "Early directions carried little selectivity but were predicted to have a large behavioral influence, while late directions carried large selectivity and little behavioral influence." }, "section_id": "section_10", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_10_evidence_package.json", "effect_size": "", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-10-persistent-activity", "source_kind": "review_finding", "source_path": "evidence/section_10_evidence_package.json", "source_refs": [ "paper:b1a3a59e-a093-4a17-a122-e55925015edb" ], "source_span": "Choice selectivity grew as it flowed through a sequence of directions in activity space.", "study_system": "mouse ALM; electrophysiology + targeted optogenetic photostimulation during memory-guided directional licking", "evidence_refs": [ { "ref": "paper:b1a3a59e-a093-4a17-a122-e55925015edb" } ], "section_title": "10. Physiological signature II — persistent activity and attractor dynamics supported by E→E recurrence (delay-period activity in mouse PFC/ALM, working memory, head-direction)", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "single_lab", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-10-persistent-activity", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_10_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }