Details

scope
mouse; cortex; in vivo, computational model; Nature communications
claim_text
Two behavioural patterns induced by circuit activation: backing away and rebound running.
section_id
section_09
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json
effect_size
In contrast, dPAG ChR2neurons, which were activated across one synapse by the optogenetic stimulation of TeAChR2fibres, exhibited a longer latency of approximately 1 s (0.956 ± 0.137 s) (Fig., middle and bottom panels; Supplementary Fig.).
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-09-amplification-isn
source_kind
review_finding
source_path
evidence/section_09_evidence_package.json
source_span
Here, we report two behavioural patterns induced by circuit activation: backing away and rebound running.
study_system
mouse; cortex; in vivo, computational model; Nature communications
section_title
9. Physiological signature I — recurrent amplification of weak inputs in mouse cortex; balanced-amplification regimes; ISN operation
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single_study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-09-amplification-isn
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
raw_fields
{
  "n": null,
  "doi": "10.1038/s41467-026-70755-y",
  "claim": "Two behavioural patterns induced by circuit activation: backing away and rebound running.",
  "cite_key": "Chen2026a",
  "evidence": "How neuronal firing within a circuit encodes behavioural intensity, like running speed, is largely unknown. Projections from temporal association cortex (TeA) and superior colliculus (SC) to dorsal periaqueductal grey (dPAG) circuit can both trigger running behaviour. Using in vivo loose-patch recordings with circuit manipulations in mice, we quantified a firing - speed relationship and established its encoding model. Here, we report two behavioural patterns induced by circuit activation: backin...",
  "effect_size": "In contrast, dPAG ChR2neurons, which were activated across one synapse by the optogenetic stimulation of TeAChR2fibres, exhibited a longer latency of approximately 1 s (0.956 ± 0.137 s) (Fig., middle and bottom panels; Supplementary Fig.).",
  "text_access": "fulltext",
  "study_system": "mouse; cortex; in vivo, computational model; Nature communications",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "Here, we report two behavioural patterns induced by circuit activation: backing away and rebound running.",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "claim_rewritten_from_source": true,
  "effect_size_source_sentence": "In contrast, dPAG ChR2neurons, which were activated across one synapse by the optogenetic stimulation of TeAChR2fibres, exhibited a longer latency of approximately 1 s (0.956 ± 0.137 s) (Fig., middle and bottom panels; Supplementary Fig.)."
}
source_refs
[
  "paper:paper-92b35fd099a1"
]
evidence_refs
[
  {
    "ref": "paper:paper-92b35fd099a1"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}
evidence_summary
How neuronal firing within a circuit encodes behavioural intensity, like running speed, is largely unknown. Projections from temporal association cortex (TeA) and superior colliculus (SC) to dorsal periaqueductal grey (dPAG) circuit can both trigger running behaviour. Using in vivo loose-patch recordings with circuit manipulations in mice, we quantified a firing - speed relationship and established its encoding model. Here, we report two behavioural patterns induced by circuit activation: backin...

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