Version history

{
  "scope": "mouse (slice ePhys + biophysical model)",
  "claim_text": "Synaptic integration in substantia nigra pars reticulata neurons reflects competition between converging direct and indirect basal ganglia inputs, modeled experimentally and computationally.",
  "raw_fields": {
    "n": null,
    "doi": "10.1073/pnas.2528602122",
    "claim": "Synaptic integration in substantia nigra pars reticulata neurons reflects competition between converging direct and indirect basal ganglia inputs, modeled experimentally and computationally.",
    "cite_key": "Thompson2025",
    "evidence": "Slice electrophysiology and computational modeling of SNr neurons in mouse.",
    "effect_size": "see source sentence",
    "text_access": "fulltext",
    "study_system": "mouse (slice ePhys + biophysical model)",
    "source_cluster_id": "cluster_02",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "It is noteworthy that the small increase in SNr activity that occurs during the prototypic pause is in line with the classical effect of the indirect pathway (to inhibit movements), whereas the postpause inhibition of the SNr would rather promote movements.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "The SNr is simulated at scale (14,000 neurons) with cell density, connectivity, afferents, and synaptic characteristics constrained by experimental data."
  },
  "section_id": "section_02",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_02_evidence_package.json",
  "effect_size": "see source sentence",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-02",
  "source_kind": "review_finding",
  "source_path": "evidence/section_02_evidence_package.json",
  "source_refs": [
    "paper:paper-361b53315aa0"
  ],
  "source_span": "It is noteworthy that the small increase in SNr activity that occurs during the prototypic pause is in line with the classical effect of the indirect pathway (to inhibit movements), whereas the postpause inhibition of the SNr would rather promote movements.",
  "study_system": "mouse (slice ePhys + biophysical model)",
  "evidence_refs": [
    {
      "ref": "paper:paper-361b53315aa0"
    }
  ],
  "section_title": "Classical Anatomy of the Triple Descending Projection",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Slice electrophysiology and computational modeling of SNr neurons in mouse.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-02",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_02_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}