In mouse dorsal presubiculum, monosynaptic excitatory inputs from anterior thal…

In mouse dorsal presubiculum, monosynaptic excitatory inputs from anterior thalamic nucleus and retrosplenial cortex converge on the same layer-3 pyramidal neurons; dual-wavelength photostimulation in slices shows spike output preferentially for near-coincident thalamic+retrosplenial inputs, providing a projection-specific cortical mechanism that anchors the head-direction attractor to visual landmarks.

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  "doi": "10.7554/elife.92443",
  "claim": "In mouse dorsal presubiculum, monosynaptic excitatory inputs from anterior thalamic nucleus and retrosplenial cortex converge on the same layer-3 pyramidal neurons; dual-wavelength photostimulation in slices shows spike output preferentially for near-coincident thalamic+retrosplenial inputs, providing a projection-specific cortical mechanism that anchors the head-direction attractor to visual landmarks.",
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  "study_system": "mouse presubiculum layer 3/4 pyramidal neurons; in-vitro dual-colour optogenetic stimulation of thalamic and retrosplenial inputs",
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  "claim_source_sentence": "Independent dual-wavelength photostimulation of these inputs in slices leads to action potential generation preferentially for near-coincident inputs, indicating that layer 3 neurons can transmit a visually matched HD signal to medial entorhinal cortex.",
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Independent dual-wavelength photostimulation of these inputs in slices leads to action potential generation preferentially for near-coincident inputs, indicating that layer 3 neurons can transmit a visually matched HD signal to medial entorhinal cortex.

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