Details

scope
mouse (whole-brain anterograde-tracer atlas)
claim_text
A whole-mouse atlas based on 138 mice receiving anterograde tracer injections maps striatal output through GPe, SNr and thalamus to identify functional domains and parallel cortico-basal-ganglia-thalamic subnetworks.
section_id
section_02
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_02_evidence_package.json
effect_size
29 striatal functional domains, 14 SNr domains, 36 GPe domains, 6 cortico-BG-thalamic subnetworks
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-02
source_kind
review_finding
source_path
evidence/section_02_evidence_package.json
source_span
A total of 138 mice were injected specifically for the striatal-output-pathway analysis, and the remainder were used for the other experiments in this manuscript.
study_system
mouse (whole-brain anterograde-tracer atlas)
section_title
Classical Anatomy of the Triple Descending Projection
evidence_summary
Multi-synaptic anterograde mapping of striatal domain output through GPe, SNr and thalamus in mouse.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-02
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_02_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 138,
  "doi": "10.1038/s41586-021-03993-3",
  "claim": "A whole-mouse atlas based on 138 mice receiving anterograde tracer injections maps striatal output through GPe, SNr and thalamus to identify functional domains and parallel cortico-basal-ganglia-thalamic subnetworks.",
  "cite_key": "Foster2021",
  "evidence": "Multi-synaptic anterograde mapping of striatal domain output through GPe, SNr and thalamus in mouse.",
  "effect_size": "29 striatal functional domains, 14 SNr domains, 36 GPe domains, 6 cortico-BG-thalamic subnetworks",
  "text_access": "fulltext",
  "study_system": "mouse (whole-brain anterograde-tracer atlas)",
  "source_cluster_id": "cluster_02",
  "replication_status": "replicated",
  "claim_source_sentence": "A total of 138 mice were injected specifically for the striatal-output-pathway analysis, and the remainder were used for the other experiments in this manuscript.",
  "replication_evidence_dois": [
    "10.1523/jneurosci.05-03-00776.1985",
    "10.1152/jn.00270.2012"
  ],
  "effect_size_source_sentence": "Accordingly, we identify 14 SNr and 36 GPe domains and a direct cortico-SNr projection."
}
source_refs
[
  "paper:paper-79995db40fc1"
]
evidence_refs
[
  {
    "ref": "paper:paper-79995db40fc1"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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