In a tractography challenge against simulated ground truth, 36 ± 17% of reconst…

In a tractography challenge against simulated ground truth, 36 ± 17% of reconstructed streamlines connected regions that were not actually connected, and 64% of bundles systematically recovered by the majority of submissions were absent from ground truth.

{
  "n": 96,
  "doi": "10.1038/s41467-017-01285-x",
  "claim": "In a tractography challenge against simulated ground truth, 36 ± 17% of reconstructed streamlines connected regions that were not actually connected, and 64% of bundles systematically recovered by the majority of submissions were absent from ground truth.",
  "cite_key": "Maier2017",
  "evidence": "Twenty research groups, 96 submitted tractograms, ground-truth phantom built from 25 major HCP-derived bundles; quantifies fundamental specificity limit of dMRI tractography.",
  "effect_size": "36 ± 17% invalid streamlines; 64% of consensus-recovered bundles were not in ground truth; precision 23 ± 9%",
  "text_access": "fulltext",
  "study_system": "Simulated whole-brain tractography phantom built from HCP global tractography; 96 tractograms from 20 groups",
  "source_cluster_id": "cluster_11",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "The MdLF, FAT, SFOF, and VOF were other examples of highly represented IBs Tractograms contained more invalid than valid bundles Across submissions, 36 ± 17% of the reconstructed individual streamlines connected regions that were not actually connected.",
  "replication_evidence_dois": [
    "10.1162/netn_a_00098",
    "10.1162/netn_a_00345",
    "10.1002/hbm.22828"
  ],
  "effect_size_source_sentence": "Across submissions, 36 ± 17% of the reconstructed individual streamlines connected regions that were not actually connected."
}

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  "paper:paper-773aecd417e5"
]

The MdLF, FAT, SFOF, and VOF were other examples of highly represented IBs Tractograms contained more invalid than valid bundles Across submissions, 36 ± 17% of the reconstructed individual streamlines connected regions that were not actually connected.

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