Details

scope
mouse motor cortex/thalamus/subiculum/hypothalamus single-neuron projection-neuron reconstruction (MouseLight)
section_id
section_01
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-01-introduction
source_kind
review_finding
source_path
evidence/section_01_evidence_package.json
study_system
mouse motor cortex/thalamus/subiculum/hypothalamus single-neuron projection-neuron reconstruction (MouseLight)
section_title
1. Introduction — what "excitatory recurrence" means operationally in mouse cortex, and why isolating it from inhibition and from clinical framings is a defensible analytic move for basic-research synthesis
evidence_summary
High-throughput whole-brain confocal imaging and semi-automated reconstruction of >1,000 sparse-labeled projection neurons in mouse motor cortex, thalamus, subiculum and hypothalamus.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-01-introduction
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (6)
claim_text
MouseLight: imaging and reconstruction of more than 1,000 projection neurons in mouse motor cortex, thalamus, subiculum and hypothalamus (totaling >85 m of axonal length) defined previously unknown projection-neuron subtypes and organizational principles of long-range connectivity.
raw_fields
{
  "n": ">1,000 neurons; >85 m axon",
  "doi": "10.1016/j.cell.2019.07.042",
  "claim": "MouseLight: imaging and reconstruction of more than 1,000 projection neurons in mouse motor cortex, thalamus, subiculum and hypothalamus (totaling >85 m of axonal length) defined previously unknown projection-neuron subtypes and organizational principles of long-range connectivity.",
  "cite_key": "Winnubst2019",
  "evidence": "High-throughput whole-brain confocal imaging and semi-automated reconstruction of >1,000 sparse-labeled projection neurons in mouse motor cortex, thalamus, subiculum and hypothalamus.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse motor cortex/thalamus/subiculum/hypothalamus single-neuron projection-neuron reconstruction (MouseLight)",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We used this platform to reconstruct more than 1,000 projection neurons in the motor cortex, thalamus, subiculum, and hypothalamus. Together, the reconstructed neurons constitute more than 85 meters of axonal length and are available in a searchable online database. Axonal shapes revealed previously unknown subtypes of projection neurons and suggest organizational principles of long-range connectivity.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:041efce6-fc13-4416-8aca-e196f82f3d70"
]
source_span
We used this platform to reconstruct more than 1,000 projection neurons in the motor cortex, thalamus, subiculum, and hypothalamus. Together, the reconstructed neurons constitute more than 85 meters of axonal length and are available in a searchable online database. Axonal shapes revealed previously unknown subtypes of projection neurons and suggest organizational principles of long-range connectivity.
evidence_refs
[
  {
    "ref": "paper:041efce6-fc13-4416-8aca-e196f82f3d70"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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