Details
- scope
- mouse somatosensory cortex; PV-Cre, VIP-Cre, SOM-Cre, NOS-Cre lines
- section_id
- section_11
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
- effect_size
- PV-Cre CBF peak at 14-18 s post-stimulation
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-11
- source_kind
- review_finding
- source_path
- evidence/section_11_evidence_package.json
- source_span
- In VIP-cre mice, photo-stimulation did not consistently produce significant changes in CBF, while slower increases in CBF that peaked 14-18 s after stimulation onset were observed in PV-cre mice.
- study_system
- mouse somatosensory cortex; PV-Cre, VIP-Cre, SOM-Cre, NOS-Cre lines
- section_title
- Cell-Type-Specific Dissection of Loop Circuits (Opto/Chemo/Tracing)
- evidence_summary
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-11
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
- claim_text
Optogenetic activation of distinct cortical interneuron classes produces differential cerebral blood flow effects: SOM-Cre and NOS-Cre activation increases CBF, PV-Cre activation produces slower CBF rises, and VIP-Cre activation produces no consistent CBF change.
- raw_fields
{ "n": 8, "doi": "10.1177/0271678x19870105", "claim": "Optogenetic activation of distinct cortical interneuron classes produces differential cerebral blood flow effects: SOM-Cre and NOS-Cre activation increases CBF, PV-Cre activation produces slower CBF rises, and VIP-Cre activation produces no consistent CBF change.", "cite_key": "Krawchuk2019", "evidence": "", "effect_size": "PV-Cre CBF peak at 14-18 s post-stimulation", "text_access": "fulltext", "study_system": "mouse somatosensory cortex; PV-Cre, VIP-Cre, SOM-Cre, NOS-Cre lines", "source_cluster_id": "cluster_10", "replication_status": "replication_unknown", "claim_source_sentence": "In VIP-cre mice, photo-stimulation did not consistently produce significant changes in CBF, while slower increases in CBF that peaked 14-18 s after stimulation onset were observed in PV-cre mice.", "replication_evidence_dois": [], "effect_size_source_sentence": "In VIP-cre mice, photo-stimulation did not consistently produce significant changes in CBF, while slower increases in CBF that peaked 14-18 s after stimulation onset were observed in PV-cre mice." }- source_refs
[ "paper:paper-09b81df57550" ]
- evidence_refs
[ { "ref": "paper:paper-09b81df57550" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }