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- Live5/17/2026, 4:35:28 PM
d5dbb578d307Content snapshot
{ "scope": "cortical circuits (review)", "claim_text": "Fast-spiking interneurons with narrow action potentials and high firing rates are essential for generating gamma frequency (30-80 Hz) oscillations in cortical circuits, with their intrinsic membrane properties tuned to resonate at gamma frequencies.", "raw_fields": { "n": 0, "doi": "10.1152/physrev.00035.2008", "claim": "Fast-spiking interneurons with narrow action potentials and high firing rates are essential for generating gamma frequency (30-80 Hz) oscillations in cortical circuits, with their intrinsic membrane properties tuned to resonate at gamma frequencies.", "evidence": "Review of experimental and computational work on cortical oscillations in cognition, establishing the role of FS interneuron intrinsic properties in gamma rhythm generation.", "effect_size": "FS interneurons essential for gamma (30-80 Hz) oscillation generation", "text_access": "abstract_only", "study_system": "cortical circuits (review)", "replication_status": "independently_replicated", "claim_source_sentence": "Synchronous rhythms represent a core mechanism for sculpting temporal coordination of neural activity in the brain-wide network.", "replication_evidence_dois": [ "10.1016/j.neuron.2016.06.033" ], "effect_size_source_sentence": "Synchronous rhythms represent a core mechanism for sculpting temporal coordination of neural activity in the brain-wide network." }, "section_id": "section_05_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_05_evidence_package.json", "effect_size": "FS interneurons essential for gamma (30-80 Hz) oscillation generation", "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-05", "source_kind": "review_finding", "source_path": "evidence/section_05_evidence_package.json", "source_refs": [ "paper:paper-b8f4cf874563" ], "source_span": "Synchronous rhythms represent a core mechanism for sculpting temporal coordination of neural activity in the brain-wide network.", "study_system": "cortical circuits (review)", "evidence_refs": [ { "ref": "paper:paper-b8f4cf874563" } ], "section_title": "Intrinsic Electrophysiology: The Fast-Spiking Phenotype and Its Variants", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "Review of experimental and computational work on cortical oscillations in cognition, establishing the role of FS interneuron intrinsic properties in gamma rhythm generation.", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "independently_replicated", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-05", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_05_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }