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- Live5/17/2026, 4:35:28 PM
196eff237ef6Content snapshot
{ "scope": "cortex/HC", "claim_text": "Characterizing optogenetically mediated rebound effects in anaesthetized mouse primary visual cortex.", "raw_fields": { "n": "", "doi": "10.1113/jp287265", "claim": "Characterizing optogenetically mediated rebound effects in anaesthetized mouse primary visual cortex.", "title": null, "cite_key": "Shapiro2025", "evidence": "Characterizing optogenetically mediated rebound effects in anaesthetized mouse primary visual cortex.. Optogenetic tools have been used to investigate neural circuits in mouse primary visual cortex (V1), where channelrhodopsin-mediated activation (photostimulation) of inhibitory interneuron subtypes expressing parvalbumin (Pvalb+), somatostatin (SOM+) or vasoactive intestinal peptide (VIP+) can alter the responses of excitatory pyramidal neurons. Some studies have mentioned rebound spiking after this photostimulation, but no systematic analysis of these post-inhibitory rebound effects has yet ", "effect_size": null, "text_access": "fulltext", "study_system": "cortex/HC", "_source_cluster": "cluster_05_synaptic_connectivity", "replication_status": "single", "_source_cluster_index": 177, "claim_source_sentence": null, "replication_evidence_dois": [] }, "section_id": "section_06", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json", "effect_size": null, "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-06-synaptic-properties", "source_kind": "review_finding", "source_path": "evidence/section_06_evidence_package.json", "source_refs": [ "paper:paper-410b852f3cc3" ], "source_span": "", "study_system": "cortex/HC", "evidence_refs": [ { "ref": "paper:paper-410b852f3cc3" } ], "section_title": "Synaptic Properties and Connectivity", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Characterizing optogenetically mediated rebound effects in anaesthetized mouse primary visual cortex.. Optogenetic tools have been used to investigate neural circuits in mouse primary visual cortex (V1), where channelrhodopsin-mediated activation (photostimulation) of inhibitory interneuron subtypes expressing parvalbumin (Pvalb+), somatostatin (SOM+) or vasoactive intestinal peptide (VIP+) can alter the responses of excitatory pyramidal neurons. Some studies have mentioned rebound spiking after this photostimulation, but no systematic analysis of these post-inhibitory rebound effects has yet ", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "single", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-06-synaptic-properties", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }