MAPseq projection mapping of 591 mouse V1 neurons showed that most neurons proj…

{
  "n": 591,
  "doi": "10.1038/nature26159",
  "claim": "MAPseq projection mapping of 591 mouse V1 neurons showed that most neurons project to multiple cortical and subcortical targets in non-random combinations.",
  "cite_key": "Han2018",
  "evidence": "Direct MAPseq evidence challenging 'one-neuron-one-area' models of intracortical projections.",
  "effect_size": "591 single V1 neurons; ≥18 cortical/subcortical target areas",
  "text_access": "abstract_only",
  "study_system": "Mouse primary visual cortex; MAPseq barcoded projection mapping",
  "source_cluster_id": "cluster_11",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Here we determine the projection patterns of 591 individual neurons in the mouse primary visual cortex using whole-brain fluorescence-based axonal tracing and high-throughput DNA sequencing of genetically barcoded neurons (MAPseq).",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2016.07.036",
    "10.1038/s41593-021-00842-4",
    "10.1038/s41467-024-52756-x"
  ],
  "effect_size_source_sentence": "Projections were highly diverse and divergent, collectively targeting at least 18 cortical and subcortical areas."
}

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  "paper:paper-236d0f50c2dd"
]

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  }
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