The findings of this meta-analysis confirm some of the conclusions of two prior…

{
  "n": null,
  "doi": "10.3389/fped.2021.685660",
  "claim": "The findings of this meta-analysis confirm some of the conclusions of two prior OCD GWASs, with glutamatergic system genes, such as GRID2, DLGAP1 , being involved in OCD pathogenesis.",
  "cite_key": "Szejko2021",
  "evidence": " (, 2021); Szejko N, Dunalska A, Lombroso A, McGuire JF, Piacentini J.",
  "effect_size": "3.2%",
  "text_access": "fulltext",
  "study_system": "Genomics of Obsessive-Compulsive Disorder-Toward Personalized Medicine in the Era of Big Data.",
  "source_cluster_id": "cluster_13",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "The findings of this meta-analysis confirm some of the conclusions of two prior OCD GWASs, with glutamatergic system genes, such as GRID2, DLGAP1 , being involved in OCD pathogenesis.",
  "replication_evidence_dois": [
    "10.1002/edm2.70228",
    "10.7754/clin.lab.2025.250572"
  ],
  "effect_size_source_sentence": "PRS for OCD was found to be significant ( p = 2 × 10 −4 ), predicting 3.2% of the phenotypic variance in an independent data set, in contrast to non-significant polygenic component in GTS, predicting only 0.6% of the phenotypic variance ( p = 0.06)."
}

[
  "paper:paper-618301298434"
]

[
  {
    "ref": "paper:paper-618301298434"
  }
]

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    "Local review repositories are read-only inputs.",
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  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
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