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1 version on record. Newest first; the live version sits at the top with a live indicator.
- Live5/17/2026, 4:35:28 PM
2e093cb7e9a1Content snapshot
{ "scope": "mouse neocortex", "claim_text": "Thus, in addition to activity-dependent processes that contribute to the developmental trajectory of VIP cells, genetic programs engaged by Prox1 control the final differentiation of multipolar and bipolar subtypes.<b>SIGNIFICANCE STATEMENT</b> The transcription factor Prox1 generates functional diversification of cortical VIP interneuron subtypes in early postnatal life, thus expanding the inhibitory repertoire of the cortex.", "raw_fields": { "n": null, "doi": "10.1523/jneurosci.1021-21.2021", "year": "2021", "claim": "Thus, in addition to activity-dependent processes that contribute to the developmental trajectory of VIP cells, genetic programs engaged by Prox1 control the final differentiation of multipolar and bipolar subtypes.<b>SIGNIFICANCE STATEMENT</b> The transcription factor Prox1 generates functional diversification of cortical VIP interneuron subtypes in early postnatal life, thus expanding the inhibitory repertoire of the cortex.", "title": null, "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "cite_key": "Stachniak2021", "evidence": "Postmitotic Prox1 Expression Controls the Final Specification of Cortical VIP Interneuron Subtypes", "effect_size": null, "text_access": "abstract_only", "study_system": "mouse neocortex", "_source_cluster": "cluster_06_disinhibition_circuit", "snowball_origin": "forward_r2", "replication_status": "replicated", "_source_cluster_index": 104, "claim_source_sentence": "Thus, in addition to activity-dependent processes that contribute to the developmental trajectory of VIP cells, genetic programs engaged by Prox1 control the final differentiation of multipolar and bipolar subtypes.<b>SIGNIFICANCE STATEMENT</b> The transcription factor Prox1 generates functional diversification of cortical VIP interneuron subtypes in early postnatal life, thus expanding the inhibitory repertoire of the cortex.", "replication_evidence_dois": [ "10.1093/cercor/bhac343", "10.1007/s00429-019-01883-z" ], "effect_size_source_sentence": null }, "section_id": "section_01", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json", "effect_size": null, "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-01-introduction", "source_kind": "review_finding", "source_path": "evidence/section_01_evidence_package.json", "source_refs": [ "paper:paper-b5b2bae45f13" ], "source_span": "Thus, in addition to activity-dependent processes that contribute to the developmental trajectory of VIP cells, genetic programs engaged by Prox1 control the final differentiation of multipolar and bipolar subtypes.<b>SIGNIFICANCE STATEMENT</b> The transcription factor Prox1 generates functional diversification of cortical VIP interneuron subtypes in early postnatal life, thus expanding the inhibitory repertoire of...", "study_system": "mouse neocortex", "evidence_refs": [ { "ref": "paper:paper-b5b2bae45f13" } ], "section_title": "Introduction", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Postmitotic Prox1 Expression Controls the Final Specification of Cortical VIP Interneuron Subtypes", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "replicated", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-01-introduction", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }