Adult mouse corticospinal layer-5 pyramidal neurons fire fast, frequency-indepe…

Adult mouse corticospinal layer-5 pyramidal neurons fire fast, frequency-independent action potentials (mean half-width 0.65 ± 0.13 ms) with linear f-I curves and regular firing — distinguishing this PT-class from neighboring callosally projecting corticostriatal IT-class neurons.

{
  "n": 0,
  "doi": "10.1093/cercor/bhs184",
  "claim": "Adult mouse corticospinal layer-5 pyramidal neurons fire fast, frequency-independent action potentials (mean half-width 0.65 ± 0.13 ms) with linear f-I curves and regular firing — distinguishing this PT-class from neighboring callosally projecting corticostriatal IT-class neurons.",
  "cite_key": "Suter2012",
  "evidence": "Slice patch-clamp recordings of retrogradely identified corticospinal neurons in young-adult mouse motor cortex.",
  "effect_size": "AP half-width 0.65 ± 0.13 ms in corticospinal neurons",
  "text_access": "abstract_only",
  "study_system": "mouse (motor cortex slice electrophysiology)",
  "source_cluster_id": "cluster_02",
  "replication_status": "replicated",
  "claim_source_sentence": "Corticospinal neurons fired relatively fast action potentials (APs; width at half-maximum 0.65 ± 0.13 ms, mean ± standard deviation [SD]) compared with neighboring callosally projecting corticostriatal neurons.",
  "replication_evidence_dois": [
    "10.1523/jneurosci.0011-12.2012",
    "10.1002/cne.23875"
  ],
  "effect_size_source_sentence": "Corticospinal neurons fired relatively fast action potentials (APs; width at half-maximum 0.65 ± 0.13 ms, mean ± standard deviation [SD]) compared with neighboring callosally projecting corticostriatal neurons."
}

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]

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