Version history

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  1. Live 609a9b71f132
    5/17/2026, 4:35:28 PM
    Content snapshot
    {
      "scope": "mouse V1",
      "claim_text": "Modulation of firing by locomotion ( Ayaz et al., 2013; Erisken et al., 2014; Fu et al., 2014; Niell and Stryker, 2010 ) has been suggested to arise from a disinhibitory circuit, where interneurons expressing vasoactive intestinal peptide ( Vip ) inhibit Sst interneurons and thereby disinhibit pyramidal (Pyr) cells.",
      "raw_fields": {
        "n": 843,
        "doi": "10.1016/j.neuron.2018.03.037",
        "year": "2018",
        "claim": "Modulation of firing by locomotion ( Ayaz et al., 2013; Erisken et al., 2014; Fu et al., 2014; Niell and Stryker, 2010 ) has been suggested to arise from a disinhibitory circuit, where interneurons expressing vasoactive intestinal peptide ( Vip ) inhibit Sst interneurons and thereby disinhibit pyramidal (Pyr) cells.",
        "title": null,
        "journal": "Neuron",
        "cite_key": "Dipoppa2018",
        "evidence": "Vision and Locomotion Shape the Interactions between Neuron Types in Mouse Visual Cortex",
        "effect_size": "300 μm",
        "text_access": "fulltext",
        "first_author": "Dipoppa",
        "study_system": "mouse V1",
        "_source_cluster": "cluster_06_disinhibition_circuit",
        "author_list_short": "Dipoppa, Ranson, Krumin",
        "replication_status": "independently_replicated",
        "_source_cluster_index": 11,
        "claim_source_sentence": "Modulation of firing by locomotion ( Ayaz et al., 2013; Erisken et al., 2014; Fu et al., 2014; Niell and Stryker, 2010 ) has been suggested to arise from a disinhibitory circuit, where interneurons expressing vasoactive intestinal peptide ( Vip ) inhibit Sst interneurons and thereby disinhibit pyramidal (Pyr) cells.",
        "replication_evidence_dois": [
          "10.1016/j.cell.2014.01.050",
          "10.7554/elife.50340"
        ],
        "effect_size_source_sentence": "The average correlation with speed was slightly negative ( ρ g r a y = − 0.05 ± 0.03 , SE) among Pvalb cells in superficial L2/3 (depth < 300 μm, n = 843) and weakly positive ( ρ g r a y = 0.11 ± 0.04 , SE , n = 831 ) in deeper L2/3. (C) Similar analysis for Vip cells. (D) Similar analysis for Sst cells."
      },
      "section_id": "section_07",
      "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json",
      "effect_size": "300 μm",
      "review_repo": "ComputationalReviewVIP",
      "section_ref": "wiki_page:computationalreviewvip-07-disinhibition-framework",
      "source_kind": "review_finding",
      "source_path": "evidence/section_07_evidence_package.json",
      "source_refs": [
        "paper:paper-f457e091013f"
      ],
      "source_span": "Modulation of firing by locomotion ( Ayaz et al., 2013; Erisken et al., 2014; Fu et al., 2014; Niell and Stryker, 2010 ) has been suggested to arise from a disinhibitory circuit, where interneurons expressing vasoactive intestinal peptide ( Vip ) inhibit Sst interneurons and thereby disinhibit pyramidal (Pyr) cells.",
      "study_system": "mouse V1",
      "evidence_refs": [
        {
          "ref": "paper:paper-f457e091013f"
        }
      ],
      "section_title": "Local Circuit Motifs and the Disinhibition Framework",
      "source_policy": {
        "mode": "public_source_pointer_with_short_context",
        "notes": [
          "Local review repositories are read-only inputs.",
          "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
        ],
        "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
        "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
      },
      "evidence_summary": "Vision and Locomotion Shape the Interactions between Neuron Types in Mouse Visual Cortex",
      "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
      "replication_status": "independently_replicated",
      "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
      "source_artifact_ref": "wiki_page:computationalreviewvip-07-disinhibition-framework",
      "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json",
      "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
      "created_by": "persona-jerome-lecoq-gbo-neuroscience",
      "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
    }