Details
- scope
- human Parkinson's disease, review
- claim_text
- In Parkinson's disease, dopamine loss is most pronounced in the posterior putamen — the territory associated with habitual control — forcing patients into reliance on the goal-directed mode mediated by rostromedial striatum.
- section_id
- section_04
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json
- effect_size
- dopamine loss predominantly in posterior putamen
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-04
- source_kind
- review_finding
- source_path
- evidence/section_04_evidence_package.json
- source_span
- In patients with Parkinson's disease the loss of dopamine is predominantly in the posterior putamen, a region of the basal ganglia associated with the control of habitual behaviour.
- study_system
- human Parkinson's disease, review
- section_title
- Striatal Output Pathways: Direct, Indirect, and Beyond
- evidence_summary
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-04
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1038/nrn2915", "claim": "In Parkinson's disease, dopamine loss is most pronounced in the posterior putamen — the territory associated with habitual control — forcing patients into reliance on the goal-directed mode mediated by rostromedial striatum.", "cite_key": "Redgrave2010a", "evidence": "", "effect_size": "dopamine loss predominantly in posterior putamen", "text_access": "abstract_only", "study_system": "human Parkinson's disease, review", "source_cluster_id": "cluster_04", "replication_status": "replicated", "claim_source_sentence": "In patients with Parkinson's disease the loss of dopamine is predominantly in the posterior putamen, a region of the basal ganglia associated with the control of habitual behaviour.", "replication_evidence_dois": [ "10.1111/j.1460-9568.2004.03095.x" ], "effect_size_source_sentence": "In patients with Parkinson's disease the loss of dopamine is predominantly in the posterior putamen, a region of the basal ganglia associated with the control of habitual behaviour." }- source_refs
[ "paper:paper-1a353ae71d6c" ]
- evidence_refs
[ { "ref": "paper:paper-1a353ae71d6c" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }