Details
- scope
- mouse, barrel cortex S1, optogenetics + laminar recording
- claim_text
- Optogenetic modulation of ~10% of local PV population mediates prominent and widespread effects on neocortical processing
- section_id
- section_08_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
- effect_size
- ~10% of PV population sufficient for prominent widespread effects
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-08
- source_kind
- review_finding
- source_path
- evidence/section_08_evidence_package.json
- source_span
- only a minor fraction (~10%) of the local PV population comprising no more than a few hundred neurons is optogenetically modulated, mediating the observed prominent and widespread effects on neocortical processing
- study_system
- mouse, barrel cortex S1, optogenetics + laminar recording
- section_title
- In Vivo Dynamics and Behavioural Correlates
- evidence_summary
- PV inhibition led to broad-spectrum power increase; whisker-evoked responses increased within 20ms; multiunit activity enhanced in neighboring columns but not at transduction site, supporting lateral inhibition role
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-08
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1093/cercor/bhx261", "claim": "Optogenetic modulation of ~10% of local PV population mediates prominent and widespread effects on neocortical processing", "evidence": "PV inhibition led to broad-spectrum power increase; whisker-evoked responses increased within 20ms; multiunit activity enhanced in neighboring columns but not at transduction site, supporting lateral inhibition role", "effect_size": "~10% of PV population sufficient for prominent widespread effects", "text_access": "abstract_only", "study_system": "mouse, barrel cortex S1, optogenetics + laminar recording", "replication_status": "replication_unknown", "claim_source_sentence": "only a minor fraction (~10%) of the local PV population comprising no more than a few hundred neurons is optogenetically modulated, mediating the observed prominent and widespread effects on neocortical processing", "replication_evidence_dois": [], "effect_size_source_sentence": "only a minor fraction (~10%) of the local PV population comprising no more than a few hundred neurons is optogenetically modulated" }- source_refs
[ "paper:paper-f450ef113660" ]
- evidence_refs
[ { "ref": "paper:paper-f450ef113660" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }