Direct and indirect pathways each bidirectionally control movement velocity in…

{
  "n": 8,
  "doi": "10.1038/nature17639",
  "claim": "Direct and indirect pathways each bidirectionally control movement velocity in a learning-dependent fashion, contradicting a strictly opposing 'go/no-go' role for the two pathways.",
  "cite_key": "Yttri2016",
  "evidence": "",
  "effect_size": "each pathway bidirectionally controls movement velocity",
  "text_access": "fulltext",
  "study_system": "mice, closed-loop cell-type-specific optogenetic stimulation during reaching",
  "source_cluster_id": "cluster_04",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Indeed, brief dMSN stimulation was sufficient to produce a significant increase in the peak velocity (1.4 cm/s increase from 29.7 cm/s; p < 7e-5; Fig.",
  "replication_evidence_dois": [
    "10.1038/nature11846",
    "10.1016/j.cell.2016.06.032"
  ],
  "effect_size_source_sentence": "Our results reveal that the direct and indirect pathways can each bidirectionally control movement velocity, demonstrating unprecedented specificity and flexibility in the control of volition by the basal ganglia."
}

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]

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